Bridging the Gap to Non-toxic Fungal Control: Lupinus-Derived Blad-Containing Oligomer as a Novel Candidate to Combat Human Pathogenic Fungi
The lack of antifungal drugs with novel modes of action reaching the clinic is a serious concern.Recently a novel antifungal protein referred to as Blad-containing oligomer (BCO) has received regulatory approval as an agricultural antifungal agent.Interestingly its spectrum of antifungal activity includes human pathogens such as Candida albicans, h